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Clinical Reviews

Chantal Autexier
Dr. Chantal Autexier discussed the role of telomeres in the maintenance of genetic and cellular integrity, and how telomere disruption is involved in cellular senescence and the aging process.
Chantal Autexier
La Dre Chantal Autexier a discuté du rôle des télomères dans le maintien de l’intégrité génétique et cellulaire, et du rôle de la perturbation des télomères dans la sénescence cellulaire et le vieillissement.
Fred Saibil
Dysphagia is frequently under-rated as a symptom by both patients and their physicians. This article highlights the common causes of dysphagia in older patients and discusses the potential contributing factors in this age group.
Oral cancer is the most common neoplasm of the head and neck and the ninth most common cancer worldwide. A simple, novel genetic test may now help with early diagnosis of this disease.
Nariman Malik
Amyotrophic lateral sclerosis was originally described by Charcot in 1874. Also known as motor neuron disease, ALS is among the most dire of the neurodegenerative diseases.
There appear to be different biochemical mechanisms that underlie neuro-degeneration in a variety of different diseases including Alzheimer's, Parkinson's, Huntington's and amyotrophic lateral sclerosis.
J. Sedmihradsky
Genetic technology has been in the news regularly in recent years, thanks to the enormous advances that have been made in the technological world.
Dr. Tomas A. Prolla, an Assistant Professor at the Departments of Genetics & Medical Genetics of the University of Wisconsin (Madison, USA), shares his thoughts on the field of "cellular markers for aging" and the implications of this research on the future of medicine and our society.
Anna Liachenko
A number of groundbreaking studies seem to suggest that only a few genes are responsible for the multiple changes in our bodies, which lead to the gradual physiological decline, we call aging.
David M. Kaplan
As the international quest to map and sequence the entire human genome continues, myriad medical conditions of a genetic origin will be recognized, and tests to identify individuals at risk for these conditions will become available.